Plus: Anthropic says it has blocked potential plots to build biological weapons. Every year, puts together our 35 Innovators Under 35, a list of some of the brightest and best young minds working across science and technology. This year's honorees include nine people transforming biotech, whose work spans everything from lifesaving innovations to groundbreaking longevity tech. Their innovations include a "reprogramming" therapy that reverses vision loss, tiny brain electrodes inspired by Japanese art, and a personalized gene-editing treatment for a baby with a rare genetic disorder. There are even efforts to design new viruses with generative AI, which (hopefully) will produce new drugs or soak up pollution. Get to know the biotech innovators behind these breakthroughs .

Every year, puts together a list of some of the brightest and best young minds working across science and technology. Our 35 Innovators Under 35 are the ones to watch--people whose research and technical work stands to shape the future of their fields. This year, the list includes nine people who are transforming biotech. And this week, I'm going to give you a taste of some of the very cool stuff five of them are working on, which includes lifesaving innovations and groundbreaking "age reversal" tech.

Plus: how a blacklisted Chinese company kept buying Nvidia's best AI chips. Our latest Innovators Under 35 list offers a glimpse. Every year, we recognize 35 people from around the world who are doing groundbreaking scientific work and building clever technical fixes for sticky problems. By finding the top young innovators globally and learning what they're focused on, we aim to give readers a sense of the advances to expect in the years to come. This year's honorees were selected from 550 nominations, with 44 expert judges helping our editors evaluate the finalists. Each works in one of four categories: biotechnology, AI, computing and robotics, and climate and energy--and has already made clear progress toward their goals.

An experimental lung disease drug developed using artificial intelligence showed promise in reversing biological signs of aging, pointing to broader potential use of the treatment, according to its developer. In a midstage study, Insilico Medicine's drug rentosertib helped reduce biological age as measured by six different aging clocks examining chemical changes in the body, according to an analysis published in Nature Biotechnology on Monday. Those who were given a placebo saw little change in their biological age on those same clocks, the Hong Kong-listed company said. "If your biological age is lower, you are likely to die later," the AI drug discovery startup's CEO, Alex Zhavoronkov, said in an interview. He cautioned that the results are still early and the long-term health effects of the drug on larger groups of people are unknown.

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Gene-edited pig kidneys could offer a lifeline to patients stuck waiting for a human donor. A woman has lived with a pig kidney for more than nine months without needing dialysis, a record-setting achievement. The woman underwent the operation at Massachusetts General Hospital on November 22 last year. As of Thursday, the kidney has been functioning for 285 days, according to Cambridge, Massachusetts-based eGenesis, the biotech company that used Crispr gene editing to make the organ fit for human transplantation. Previously, the record for a person living with a transplanted pig kidney was 271 days, set by Tim Andrews. Most people in need of a kidney transplant wait three to five years on average to receive one, though it can take longer depending on blood type and other factors.

Across the world, hundreds of people have come to believe they have made extraordinary scientific discoveries with AI chatbots such as ChatGPT, Claude and Gemini. Others say their AI has'awakened', or is leading them to a higher spiritual realm. The Guardian journalist Michael Safi begins investigating a phenomenon labelled'AI psychosis', travelling to the US to meet two people who have been on weird journeys with their chatbots

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How an alliance of tech startups, MAHA operatives, and actual medical experts made millennial women the new face of hormone therapy. Lisa Schrenk didn't know it yet, as she trudged down a dirt trail last August, but her life was about to change. She'd set out late the night before with her hiking group, scrambling up Virginia's Old Rag Mountain in darkness. They reached the peak in time to watch the sun rise over the Blue Ridge range. Afterward, the women snapped photos. In one, Schrenk gazes out over the horizon, her long dark hair pulled into a ponytail. The image is deceptively triumphant. In reality, she had been contemplating suicide. Schrenk, a longtime IT specialist for the federal government, had started setting aside belongings for friends and family, organizing her financial affairs, and clearing out her office.